Developing Reference Methods for Nanomaterials
The EU FP7 large-scale integrating project NanoValid (contract: 263147) has been launched on the 1st of November 2011, as one of the "flagship" nanosafety projects. The project consists of 24 European partners from 14 different countries and 6 partners from Brazil, Canada, India and the US and will run from 2011 to 2015, with a total budget of more than 13 mio EUR (EC contribution 9.6 mio EUR). Main objective of NanoValid is to develop a set of reliable reference methods and materials for the fabrication, physicochemical (pc) characterization, hazard identification and exposure assessment of engineered nanomaterials (EN), including methods for dispersion control and labelling of ENs. Based on newly established reference methods, current approaches and strategies for risk and life cycle assessment will be improved, modified and further developed, and their feasibility assessed by means of practical case studies.
In cooperation with other relevant projects, such as MARINA and QNano, and relevant standardization bodies, such as the OECD WPMN, existing industrial or newly designed ENs will be subjected to a rigid and comprehensive inter-laboratory validation campaign that includes the currently most advanced methods and instruments for measuring and characterizing of ENs, to generate accurate and reproducible material data and standardized method protocols, also for tracing and quantifying nanoparticles (NP) in complex matrices. The stability and behaviour of selected NP will be monitored and tested in a variety of relevant environmental samples and test media to derive optimum and reproducible fabrication, measurement and test conditions.
The validated characterization methods will be used to design well-defined certified reference materials, which in turn will help to validate, adapt, modify and further develop current biological approaches (in vitro, in vivo and in silico) for assessing hazard and exposure of ENs, and associated risks to human health and the environment. Effects of chronic and accumulative exposure and of exposure under real-life conditions, where ENPs are likely to act as components of complex mixtures, will be duly taken into account.
Rudolf Reuther, Coordinator, email: firstname.lastname@example.org
Nanosciences, nanotechnologies, materials and new production technologies
FP7 Project with U.S. partner
Brazil, Canada, EU, India, USA